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Mouse Anti-SMS Recombinant Antibody (1G6) (CBMAB-A8389-LY)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
1G6
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
SMS (AAH09898.1, 1 a.a. ~ 366 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
spermine synthase
Introduction
The protein encoded by this gene belongs to the spermidine/spermine synthases family. This gene encodes an ubiquitous enzyme of polyamine metabolism. [provided by RefSeq]
Entrez Gene ID
UniProt ID
Alternative Names
MRSR; SPMSY; SRS; SpS
Function
Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM).
Biological Process
Biological Process methionine metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process polyamine metabolic processTAS:Reactome
Biological Process spermine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytosol
extracellular exosome
Involvement in disease
Intellectual developmental disorder, X-linked, syndromic, Snyder-Robinson type (MRXSSR):
An X-linked intellectual disability syndrome characterized by a collection of clinical features including facial asymmetry, marfanoid habitus, hypertonia, osteoporosis and unsteady gait.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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