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Rat Anti-SEMA3C Recombinant Antibody (MM0607-29U11) (CBMAB-0808CQ)


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Summary

Host Animal
Rat
Specificity
Human
Clone
MM0607-29U11
Antibody Isotype
IgG2
Application
IHC-Fr, WB

Basic Information

Immunogen
Recombinant Human Semaphorin 3c
Specificity
Human
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Introduction
This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance.
Entrez Gene ID
10512
UniProt ID
Q99985
Alternative Names
SemE; SEMAE
Function
Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).
Biological Process
Biological Process axon guidanceISS:UniProtKB
Biological Process blood vessel remodelingIEA:Ensembl
Biological Process cardiac endothelial to mesenchymal transitionIEA:Ensembl
Biological Process cardiac right ventricle morphogenesisIEA:Ensembl
Biological Process dichotomous subdivision of terminal units involved in salivary gland branchingIEA:Ensembl
Biological Process immune responseManual Assertion Based On ExperimentTAS:ProtInc
Biological Process limb bud formationIEA:Ensembl
Biological Process negative chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of axon extension involved in axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neural crest cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neural tube developmentIEA:Ensembl
Biological Process outflow tract septum morphogenesisISS:BHF-UCL
Biological Process positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesisISS:BHF-UCL
Biological Process positive regulation of cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process post-embryonic developmentIEA:Ensembl
Biological Process pulmonary myocardium developmentIEA:Ensembl
Biological Process response to xenobiotic stimulusManual Assertion Based On ExperimentTAS:ProtInc
Biological Process semaphorin-plexin signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process somitogenesisIEA:Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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