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Recombinant Mouse Anti-SCG2 Recombinant Antibody (9G3/3) (CBMAB-XB1026-YC)


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Summary

Host Animal
Mouse
Specificity
Mouse, Rat
Clone
9G3/3
Antibody Isotype
IgG2b
Application
FC, IHC, IP, WB

Basic Information

Specificity
Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
secretogranin II (chromogranin C)
Introduction
SCG2 is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin.
Entrez Gene ID
Rat24765
Mouse20254
UniProt ID
RatP10362
MouseQ03517
Alternative Names
Secretogranin II; Chromogranin-C; Secretoneurin; CHGC; SgII; Secretogranin-2; Chromogranin C; EM66; SN;
Function
Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
Biological Process
Biological Process angiogenesisManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process endothelial cell migrationManual Assertion Based On ExperimentTAS:HGNC-UCL
Biological Process eosinophil chemotaxisManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process induction of positive chemotaxisManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process inflammatory responseManual Assertion Based On ExperimentTAS:HGNC-UCL
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process MAPK cascadeManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process negative regulation of endothelial cell apoptotic processManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process negative regulation of endothelial cell proliferationManual Assertion Based On ExperimentTAS:HGNC-UCL
Biological Process negative regulation of extrinsic apoptotic signaling pathwayManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive chemotaxisManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of endothelial cell proliferationManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process protein secretionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
Neuroendocrine and endocrine secretory granules.
PTM
O-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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