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Mouse Anti-S100A2 Recombinant Antibody (SH-L1) (CBMAB-S6563-CQ)


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Summary

Host Animal
Mouse
Specificity
Cattle, Dog, Cat, Goat, Human, Pig, Rat, Reptile
Clone
SH-L1
Antibody Isotype
IgG1
Application
ELISA, ICC, IF, IP, WB

Basic Information

Immunogen
Purified, full length, native pig protein
Specificity
Cattle, Dog, Cat, Goat, Human, Pig, Rat, Reptile
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Ascites fluid
Preservative
15 mM sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
S100 Calcium Binding Protein A2
Introduction
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.
Entrez Gene ID
Human6273
Cat101082878
Rat100910139
Pig100152729
Cattle509860
Dog612326
Goat102189534
UniProt ID
HumanP29034
CatM3WUI8
PigK7GQ95
CattleP10462
DogA0A8C0QDJ3
GoatA0A452EBP2
Alternative Names
S100 Calcium Binding Protein A2; S100 Calcium-Binding Protein A2; S100L; CAN19; Protein S100-A2; Protein S-100L;
Function
May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth.
Biological Process
Endothelial cell migration
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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