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Mouse Anti-RRP7A Recombinant Antibody (B-4) (CBMAB-R3705-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
B-4
Application
WB, IP, IF, IHC-P, ELISA

Basic Information

Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
Ribosomal RNA Processing 7 Homolog A
Introduction
RRP7A (Ribosomal RNA Processing 7 Homolog A) is a Protein Coding gene. Among its related pathways are Gene Expression and rRNA processing in the nucleus and cytosol. Gene Ontology (GO) annotations related to this gene include nucleotide binding.
Entrez Gene ID
27341
UniProt ID
Q9Y3A4
Alternative Names
Ribosomal RNA Processing 7 Homolog A; Gastric Cancer Antigen Zg14; Ribosomal RNA Processing 7 Homolog A (S. Cerevisiae); Ribosomal RNA-Processing Protein 7 Homolog A; CTA-126B4.5; BK126B4.3; CGI-96; Rrp7;
Function
Nucleolar protein that is involved in ribosomal RNA (rRNA) processing (PubMed:33199730).
Also plays a role in primary cilia resorption, and cell cycle progression in neurogenesis and neocortex development (PubMed:33199730).
Biological Process
Biological Process blastocyst formationIEA:Ensembl
Biological Process cilium disassemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein localization to nucleolusManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process ribosomal small subunit assemblyManual Assertion Based On ExperimentIBA:GO_Central
Biological Process ribosome biogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process rRNA processingManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus, nucleolus
Cell projection, cilium
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Involvement in disease
Microcephaly 28, primary, autosomal recessive (MCPH28):
A form of microcephaly, a disease defined as a head circumference more than 3 standard deviations below the age, sex and ethnically matched mean. Brain weight is markedly reduced and the cerebral cortex is disproportionately small. MCPH28 is an autosomal recessive form characterized by reduced head size (down to -8 SD) and variably impaired intellectual development apparent from early childhood.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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