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Mouse Anti-RNF17 Monoclonal Antibody (1B9) (CBMAB-0053-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1B9
Antibody Isotype
IgG2c
Application
IP, ELISA, WB

Basic Information

Immunogen
Recombinant peptide (Full Length)
Specificity
Human
Antibody Isotype
IgG2c
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
RNF17
Introduction
This gene encodes a testis-specific protein, which is similar to a mouse gene containing a RING finger domain. Alternatively, spliced transcript variants encoding different isoforms have been found.
Entrez Gene ID
56163
UniProt ID
Q9BXT8
Alternative Names
FLJ11045; Mmip-2; SPATA23; TDRD4
Function
Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad-MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity).
Biological Process
Spermatid development
Cellular Location
Cytoplasm
Nucleus
Predominantly found in the cytoplasm. Component of a nuage in male germ cells (an electron-dense spherical cytoplasmic body present in late pachytene and diplotene spermatocytes and in elonging spermatids) (By similarity).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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