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Rat Anti-RETN Recombinant Antibody (175322) (CBMAB-R2239-CN)


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Summary

Host Animal
Rat
Specificity
Mouse
Clone
175322
Antibody Isotype
IgG1
Application
WB, ELISA

Basic Information

Immunogen
E. coli-derived recombinant mouse Resistin, Ser21-Ser114, Accession # Q99P87
Specificity
Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
LYOPH
Buffer
PBS, Trehalose
Concentration
LYOPH

Target

Full Name
Resistin
Introduction
This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
Entrez Gene ID
57264
UniProt ID
Q99P87
Alternative Names
Resistin; C/EBP-Epsilon-Regulated Myeloid-Specific Secreted Cysteine-Rich Protein; Cysteine-Rich Secreted Protein A12-Alpha-Like 2; Adipose Tissue-Specific Secretory Factor; Cysteine-Rich Secreted Protein FIZZ3; FIZZ3; ADSF; RSTN;
Function
Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells (By similarity).
Potentially links obesity to diabetes (By similarity).
Promotes chemotaxis in myeloid cells (PubMed:15064728).
Biological Process
Biological Process agingIEA:Ensembl
Biological Process fat cell differentiationIEA:Ensembl
Biological Process negative regulation of feeding behaviorIEA:Ensembl
Biological Process positive regulation of progesterone secretionIEA:Ensembl
Biological Process positive regulation of synaptic transmissionIEA:Ensembl
Biological Process response to insulinIEA:Ensembl
Biological Process response to mechanical stimulusIEA:Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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