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Rabbit Anti-RABAC1 Recombinant Antibody (CBCNR-079) (CBMAB-R0960-CN)


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Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBCNR-079
Antibody Isotype
IgG
Application
WB, IP, FC

Basic Information

Immunogen
A synthetic peptide corresponding to residues near the C-terminus of human PRA1
Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
49% PBS, 50% Glycerol, 0.05% BSA
Preservative
0.01% Sodium azide

Target

Full Name
Rab acceptor 1 (prenylated)
Introduction
RABAC1 (Rab Acceptor 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include identical protein binding and proline-rich region binding.
Entrez Gene ID
Human10567
Mouse14470
Rat83583
UniProt ID
HumanQ9UI14
MouseQ9Z0S9
RatO35394
Alternative Names
Rab Acceptor 1; Rab Acceptor 1 (Prenylated); Prenylated Rab Acceptor 1; PRA1 Family Protein 1; PRA1 Domain Family 1; PRAF1; PRA1; Prenylated Rab Acceptor Protein 1; YIP3;
Function
General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI.
Cellular Location
Cell membrane
Cytoplasm
Golgi apparatus
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle
According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles.
Topology
Cytoplasmic: 1-78
Helical: 79-112
Cytoplasmic: 113-131
Helical: 132-165
Cytoplasmic: 166-185
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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