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Mouse Anti-NPFFR1 Recombinant Antibody (2A10) (CBMAB-N3123-WJ)

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Summary

Host Animal
Mouse
Specificity
Human, Rat
Clone
2A10
Antibody Isotype
IgG1, κ
Application
ELISA, IHC

Basic Information

Specificity
Human, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
0.25 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Neuropeptide FF Receptor 1
Introduction
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Entrez Gene ID
Human64106
Rat64107
UniProt ID
HumanQ9GZQ6
RatQ9EP86
Alternative Names
Neuropeptide FF Receptor 1; RFamide-Related Peptide Receptor OT7T022; G-Protein Coupled Receptor 147; Neuropeptide FF 1; GPR147; NPFF1; G Protein-Coupled Receptor 147; NPFF1R1; OT7T022;
Function
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Biological Process
G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-43
Helical: 44-64
Cytoplasmic: 65-80
Helical: 81-101
Extracellular: 102-117
Helical: 118-138
Cytoplasmic: 139-158
Helical: 159-179
Extracellular: 180-214
Helical: 215-235
Cytoplasmic: 236-271
Helical: 272-292
Extracellular: 293-307
Helical: 308-328
Cytoplasmic: 329-430
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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