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Mouse Anti-NDUFB4 Recombinant Antibody (17G3D9E12) (CBMAB-N1653-WJ)


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Summary

Host Animal
Mouse
Specificity
Rat, Cattle, Human
Clone
17G3D9E12
Antibody Isotype
IgG1
Application
WB, IHC-P, FC, ICC

Basic Information

Specificity
Rat, Cattle, Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
NADH:Ubiquinone Oxidoreductase Subunit B4
Introduction
This gene encodes a non-catalytic subunit of the multisubunit NADH:ubiquinone oxidoreductase, the first enzyme complex in the mitochondrial electron transport chain (complex I). Mammalian complex I is composed of 45 different subunits and transfers electrons from NADH to ubiquinone. [provided by RefSeq, Dec 2009]
Entrez Gene ID
Human4710
Cattle327706
Rat288088
UniProt ID
HumanO95168
CattleP48305
RatF1LPG5
Alternative Names
NADH:Ubiquinone Oxidoreductase Subunit B4; NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 4, 15kDa; NADH-Ubiquinone Oxidoreductase B15 Subunit; Complex I B15 Subunit; Complex I-B15; CI-B15; NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 4 (15kD, B15); NADH Dehydrogenase [Ubiquinone] 1 Beta Subcomplex Subunit 4; B15;
Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Biological Process
Aerobic respiration Source: ComplexPortal
Mitochondrial ATP synthesis coupled proton transport Source: ComplexPortal
Mitochondrial electron transport, NADH to ubiquinone Source: UniProtKB
Mitochondrial respiratory chain complex I assembly Source: UniProtKB
Response to oxidative stress Source: UniProtKB
Cellular Location
Mitochondrion inner membrane
Topology
Helical: 88-105
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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