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Rabbit Anti-NAPSA Recombinant Antibody (RM366) (CBMAB-BR366LY)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
RM366
Antibody Isotype
IgG
Application
WB: 0.1-0.5 μg/ml

Basic Information

Immunogen
A peptide corresponding to the N-terminus of human Napsin-A
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol, 1% BSA
Preservative
0.09% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Napsin A Aspartic Peptidase
Introduction
This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]
Entrez Gene ID
9476
UniProt ID
O96009
Alternative Names
Napsin-A;3.4.23.-;Aspartyl protease 4;ASP4;Asp 4;Napsin-1;TA01/TA02;NAPSA;NAP1, NAPA;
Function
May be involved in processing of pneumocyte surfactant precursors.
Biological Process
Membrane protein proteolysis Source: UniProtKB
Proteolysis Source: UniProtKB
Surfactant homeostasis Source: UniProtKB
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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