Mouse Anti-MIOX Recombinant Antibody (CBFYM-2233) (CBMAB-M2416-FY)

Name: Mouse Anti-MIOX Recombinant Antibody (CBFYM-2233)
SKU: CBMAB-M2416-FY
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYM-2233

Antibody Isotype

IgG2a

Application

FC, IF, IHC, WB

Basic Information

Immunogen

Full length recombinant protein of human MIOX (NP_060054) produced in HEK293T cells

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% Sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

MYO-INOSITOL OXYGENASE

Introduction

MIOX is a Protein Coding gene. Among its related pathways are Porphyrin and chlorophyll metabolism and Inositol phosphate metabolism. Gene Ontology annotations related to this gene include iron ion binding and oxidoreductase activity, acting on NADH.

Entrez Gene ID

55586

UniProt ID

Q9UGB7

Alternative Names

Myo-Inositol Oxygenase; Kidney-Specific Protein 32; Aldehyde Reductase (Aldose Reductase) Like 6; Renal-Specific Oxidoreductase; Aldehyde Reductase-Like 6; MI Oxygenase

Biological Process

Inositol catabolic process Source: UniProtKB

Cellular Location

Cytoplasm

More Infomation

References

Guo, W., Yu, D., Zhang, R., Zhao, W., Zhang, L., Wang, D., ... & Guo, C. (2023). Genome-wide identification of the myo-inositol oxygenase gene family in alfalfa (Medicago sativa L.) and expression analysis under abiotic stress. Plant Physiology and Biochemistry, 200, 107787.

Yang, J., Yang, J., Zhao, L., Gu, L., Wu, F., Tian, W., ... & Wang, L. (2021). Ectopic expression of a Malus hupehensis Rehd. myo-inositol oxygenase gene (MhMIOX2) enhances tolerance to salt stress. Scientia Horticulturae, 281, 109898.

Marques, W. L., Anderson, L. A., Sandoval, L., Hicks, M. A., & Prather, K. L. (2020). Sequence-based bioprospecting of myo-inositol oxygenase (Miox) reveals new homologues that increase glucaric acid production in Saccharomyces cerevisiae. Enzyme and Microbial Technology, 140, 109623.

Sharma, I., Deng, F., Liao, Y., & Kanwar, Y. S. (2020). Myo-inositol oxygenase (MIOX) overexpression drives the progression of renal tubulointerstitial injury in diabetes. Diabetes, 69(6), 1248-1263.

Munir, S., Mumtaz, M. A., Ahiakpa, J. K., Liu, G., Chen, W., Zhou, G., ... & Zhang, Y. (2020). Genome-wide analysis of Myo-inositol oxygenase gene family in tomato reveals their involvement in ascorbic acid accumulation. BMC genomics, 21(1), 1-15.

Tominaga, T., Sharma, I., Fujita, Y., Doi, T., Wallner, A. K., & Kanwar, Y. S. (2019). Myo-inositol oxygenase accentuates renal tubular injury initiated by endoplasmic reticulum stress. American Journal of Physiology-Renal Physiology, 316(2), F301-F315.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
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Second antibody and isotype control

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