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Mouse Anti-MAATS1 Recombinant Antibody (CBWJC-4129) (CBMAB-C5473WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJC-4129
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
Human recombinant protein fragment corresponding to aa1-313 of human C3orf15 (NP_203528) produced in E.coli
Specificity
Human
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS (PH 7.3), 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MYCBP Associated And Testis Expressed 1
Introduction
MAATS1 (MYCBP Associated And Testis Expressed 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include adenosylmethionine decarboxylase activity.
Entrez Gene ID
89876
UniProt ID
Q7Z4T9
Alternative Names
MYCBP Associated And Testis Expressed 1; AMY-1-Associating Protein Expressed In Testis 1; MYCBP/AMY-1-Associated Testis-Expressed Protein 1; MYCBP/AMY-1-Associated, Testis Expressed 1; MYCBP-Associated, Testis Expressed 1; Spermatogenesis Associated 26; MYCBP-Binding Protein; Protein MAATS1; C3orf15; CFAP91;
Function
Involved in sperm flagellum axonemal organization and function (PubMed:12223483, PubMed:32161152).
May regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).
Biological Process
Axonemal central apparatus assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Cilium movementISS:UniProtKB
SpermatogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Mitochondrion
Cytoplasm
Cytoplasm, cytoskeleton, cilium axoneme
Localized in the neck of the sperm.
Isoform 7:
Cytoplasm
Involvement in disease
Spermatogenic failure 51 (SPGF51):
An autosomal recessive infertility disorder characterized by asthenoteratozoospermia. Spermatozoa exhibit multiple morphologic abnormalities, including absent, short, bent, coiled and irregular-caliber flagella. Abnormalities of the sperm head, base, and acrosome have also been observed.
PTM
Phosphorylated by PKA.
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For research use only. Not intended for any clinical use.

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