Recombinant Mouse Anti-LGALS2 Antibody (CBHb321) (CBMAB-Hb494-LY)

See all LGALS2 antibodies

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human, Mouse

Clone

CBHb321

Antibody Isotype

IgG1

Application

FC, Immuno assays

Basic Information

Immunogen

Recombinant human galectin-2

Specificity

Human, Mouse

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

0.1% BSA

Preservative

0.02% sodium azide

Concentration

0.1 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Galectin 2

Entrez Gene ID

Human	3957
Mouse	107753

UniProt ID

Human	P05162
Mouse	Q9CQW5

Alternative Names

Beta-galactoside-binding lectin L-14-II, HL14, Lactose-binding lectin 2, S-Lac lectin 2

Function

This protein binds beta-galactoside. Its physiological function is not yet known.

Biological Process

Cell-cell adhesionManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of apoptotic processManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of inflammatory responseIEA:Ensembl
T cell homeostasisManual Assertion Based On ExperimentIDA:ComplexPortal

Cellular Location

Cytoplasm
Galectin complex

More Infomation

References

He, S., Ji, Z., Zhang, Q., Zhang, X., Chen, J., Hu, J., ... & Ding, Y. (2023). Investigation of LGALS2 expression in the TCGA database reveals its clinical relevance in breast cancer immunotherapy and drug resistance. Scientific Reports, 13(1), 17445.

Jiang, H., Sun, Q., Huang, Z., Chen, H., Chen, L., & He, X. (2023). LGALS2 and EGR1: markers of endometriosis for predictive, preventive and personalized medicine.

Ji, P., Gong, Y., Jin, M. L., Wu, H. L., Guo, L. W., Pei, Y. C., ... & Shao, Z. M. (2022). In vivo multidimensional CRISPR screens identify Lgals2 as an immunotherapy target in triple-negative breast cancer. Science Advances, 8(26), eabl8247.

Chetry, M., Bhandari, A., Feng, R., Song, X., Wang, P., & Lin, J. (2022). Overexpression of galectin2 (LGALS2) predicts a better prognosis in human breast cancer. American Journal of Translational Research, 14(4), 2301.

Xu, D., Guo, L., Zhang, S., & Hou, Q. (2022). LGALS2 suppresses the progression of papillary thyroid carcinoma by regulating the PI3K/AKT pathway. Gland Surgery, 11(9), 1518.

Xu, W. D., Wu, Q., He, Y. W., Huang, A. F., Lan, Y. Y., Fu, L., ... & Liu, X. Y. (2021). Gene polymorphisms of LGALS2, LGALS3 and LGALS9 in patients with rheumatoid arthritis. Cellular Immunology, 368, 104419.

Li, H., Zhao, L., Lau, Y. S., Zhang, C., & Han, R. (2021). Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth. Oncogene, 40(1), 177-188.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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