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Mouse Anti-LALBA Recombinant Antibody (EC12) (V2LY-0624-LY12)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
EC12
Antibody Isotype
IgG
Application
WB, IHC-P, IF

Basic Information

Immunogen
Synthetic Peptide.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
IHC-P1:50-1:300
IF(CC)1:100-1:300

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 50% glycerol
Preservative
0.02% sodium azide
Concentration
Batch dependent
Purity
>95% by SDS Page
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Lactalbumin Alpha
UniProt ID
P00709
Function
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
Biological Process
Apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Defense response to bacteriumManual Assertion Based On ExperimentTAS:ProtInc
Lactose biosynthetic processManual Assertion Based On ExperimentTAS:ProtInc
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
More Infomation

Čítek, J., Samková, E., Brzáková, M., Hanuš, O., Večerek, L., Hoštičková, I., ... & Hálová, K. (2023). CSN1S1 and LALBA Polymorphisms and Other Factors Influencing Yield, Composition, Somatic Cell Score, and Technological Properties of Cow’s Milk. Animals, 13(13), 2079.

Sallam, A. M. (2023). Effect of genetic polymorphisms in LALBA and Prolactin genes on milk traits in Barki ewes. Small Ruminant Research, 226, 107041.

Fan, X. Y., Qiu, L. H., Zhang, Y. Y., Teng, X. H., & Miao, Y. W. (2021). Polymorphism, molecular characteristics of alpha-lactalbumin (LALBA) gene in river and swamp buffalo. Russian Journal of Genetics, 57, 836-846.

Ostrowska, M., Zwierzchowski, L., Brzozowska, P., Kawecka-Grochocka, E., Żelazowska, B., & Bagnicka, E. (2021). The effect of single-nucleotide polymorphism in the promoter region of bovine alpha-lactalbumin (LALBA) gene on LALBA expression in milk cells and milk traits of cows. Journal of Animal Science, 99(7), skab169.

Manzoor, S., Nadeem, A., & Javed, M. (2020). Polymorphism association and expression analysis of alpha-lactalbumin (LALBA) gene during lactation in Nili Ravi buffalo. Tropical Animal Health and Production, 52(1), 265-271.

Soyudal, B., Ardıçlı, S. E. N. A., Şamlı, H. A. L. E., Dinçel, D. E. N. İ. Z., & Balcı, F. (2019). Association of polymorphisms in the CSN2, CSN3, LGB and LALBA genes with milk production traits in Holstein cows raised in Turkey. Journal of the Hellenic Veterinary Medical Society, 69(4).

Crisà, A., Claps, S., Moioli, B., & Marchitelli, C. (2019). Identification of the complete coding cDNAs and expression analysis of B4GALT1, LALBA, ST3GAL5, ST6GAL1 in the colostrum and milk of the Garganica and Maltese goat breeds to reveal possible implications for oligosaccharide biosynthesis. BMC veterinary research, 15(1), 1-14.

Houaga, I. (2018). Polymorphisms in major milk protein genes (LALBA, MBLG, CSN1S1 and CSN3) and milk fat genes (DGAT1 and SCD1) and association with milk production and fatty acid traits in indigenous White Fulani and Borgou cattle breeds in Benin (Doctoral dissertation, JKUAT).

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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