Mouse Anti-KCMF1 Recombinant Antibody (2483C5a) (CBMAB-K0464-LY)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

2483C5a

Antibody Isotype

IgG2a

Application

Dot Blot, ICC

Basic Information

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

KCMF1

Introduction

Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

Entrez Gene ID

56888

UniProt ID

Q9P0J7

Alternative Names

Potassium Channel Modulatory Factor 1; RING-Type E3 Ubiquitin Transferase KCMF1; ZZ-Type Zinc Finger-Containing Protein 1; FGF-Induced In Gastric Cancer; FIGC; PCMF; ZZZ1; FGF-Induced Ubiquitin-Protein Ligase In Gastric Cancers;

Function

Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

Biological Process

Synaptic signalingManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytosol; Extracellular region; Ficolin-1-rich granule lumen; Plasma membrane; Synapse

More Infomation

References

Singh, A., Choudhury, S. D., Singh, P., Singh, V. V., Singh, S. N., & Sharma, A. (2023). KCMF1 regulates autophagy and ion channels’ function in renal cell carcinoma: a future therapeutic target. Journal of Cancer Research and Clinical Oncology, 149(9), 5617-5626.

Kong, T., Fang, Y., Fan, X., & Li, S. (2023). KCMF1-like suppresses white spot syndrome virus infection by promoting apoptosis in mud crab (Scylla paramamosain). Fish & Shellfish Immunology, 109158.

Singh, A., Choudhury, S. D., Singh, P., Kaushal, S., & Sharma, A. (2023). Disruption in networking of KCMF1 linked ubiquitin ligase impairs autophagy in CD8+ memory T cells of patients with renal cell carcinoma. Cancer Letters, 564, 216194.

Wang, W., Liu, J., & Pan, E. (2022). CircHIPK3 contributes to human villous trophoblast growth, migration and invasion via modulating the pathway of miR-346/KCMF1. Placenta, 118, 46-54.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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