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Rabbit Anti-HMG20B Recombinant Antibody (EG1524) (CBMAB-EN1823-LY)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG1524
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:20000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from N-terminal of human HMG20B.
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
High Mobility Group 20B
Introduction
HMG20B (High Mobility Group 20B) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and chromatin binding. An important paralog of this gene is HMG20A.
Entrez Gene ID
10362
UniProt ID
Q9P0W2
Alternative Names
High Mobility Group 20B; Structural DNA-Binding Protein BRAF35; HMG Domain-Containing Protein HMGX2; HMG Domain-Containing Protein 2; Sox-Like Transcriptional Factor; HMG Box-Containing Protein 20B; HMG Box Domain Containing 2; BRCA2-Associated Factor 35; SMARCE1-Related Protein; SMARCE1r; BRAF35;
Function
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
Biological Process
Cell cycle Source: UniProtKB-KW
Chromatin organization Source: UniProtKB-KW
Negative regulation of protein sumoylation Source: Ensembl
Positive regulation of neuron differentiation Source: Ensembl
Regulation of gene expression Source: GO_Central
Skeletal muscle cell differentiation Source: Ensembl
Cellular Location
Nucleus; Chromosome. Localized to condensed chromosomes in mitosis in conjunction with BRCA2.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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