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Rabbit Anti-H4C1 Recombinant Antibody (CBYJT-1372) (CBMAB-T0394-YJ)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBYJT-1372
Antibody Isotype
IgG
Application
ChIP, FC, ICC, IF, Peptide Array, WB

Basic Information

Immunogen
Methylated peptide (Lys20) corresponding to Human H4 (aa 18-26)
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Preservative
0.09% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 18-26

Target

Full Name
H4C1
Introduction
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST1H4A is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from HIST1H4A lack polyA tails but instead contain a palindromic termination element. HIST1H4A is found in the large histone gene cluster on chromosome 6.
Entrez Gene ID
8359
UniProt ID
P62805
Alternative Names
Histone Cluster 1 H4 Family Member A; H4 Histone Family, Member A; Histone Cluster 1, H4a; Histone 1, H4a; H4FA; HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H4A HIST2H4B HIST4H4; Histone H4; HIST2H4; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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