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Mouse Anti-H4C1 (Acetylated K12) Recombinant Antibody (3HH4-4C10) (PTM-CBMAB-0380LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3HH4-4C10
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Immunogen
Synthetic peptide corresponding to amino acids 1-24 of human Histone H4 coupled to ovalbumin: MSGRG(acetyl-K)GG(acetyl-K) GLG(acetyl-K)GGA(acetyl-K)RHRKVLR-C
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Antibody in ascites with 0.05% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
H4C1
Introduction
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
Entrez Gene ID
8359
UniProt ID
P62805
Alternative Names
Histone Cluster 1 H4 Family Member A; H4 Histone Family, Member A; Histone Cluster 1, H4a; Histone 1, H4a; H4FA; HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H4A HIST2H4B HIST4H4; Histone H4; HIST2H4; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K;
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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