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Mouse Anti-GLUD2 Recombinant Antibody (848209) (CBMAB-G0538-LY)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
848209
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
E. coli-derived recombinant human GLUD1/GLUD2, Ser54-Thr558, Accession # P49448
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
lyophilized
Buffer
Trehalose
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
glutamate dehydrogenase 2
Introduction
The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.[provided by RefSeq, Jan 2010]
Entrez Gene ID
Human2747
Mouse14804
Rat79220
UniProt ID
HumanP49448
MouseQ61625
RatQ63226
Alternative Names
Glutamate Dehydrogenase 2; Glutamate Dehydrogenase Pseudogene 1; EC 1.4.1.3; GLUDP1; GDH 2; Glutamate Dehydrogenase 2; Mitochondrial; Testicular Secretory Protein Li 14; EC 1.4.1; GDH2;
Function
Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission.
Biological Process
Glutamate biosynthetic process Source: BHF-UCL
Glutamate catabolic process Source: BHF-UCL
Glutamate metabolic process Source: UniProtKB
Cellular Location
Mitochondrion matrix
PTM
Stoichiometry shows that ADP-ribosylation occurs in one subunit per catalytically active homohexamer.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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