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Mouse Anti-GART Recombinant Antibody (4D6-1D5) (CBMAB-G0205-LY)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
4D6-1D5
Antibody Isotype
IgG1, κ
Application
ELISA, IF, IHC, WB

Basic Information

Immunogen
Recombinant corresponding to aa1-434 from human GART with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.5 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Phosphoribosylglycinamide Formyltransferase, Phosphoribosylglycinamide Synthetase, Phosphoribosylaminoimidazole Synthetase
Introduction
The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Entrez Gene ID
UniProt ID
Alternative Names
Phosphoribosylglycinamide Formyltransferase; Phosphoribosylglycinamide Synthetase; Phosphoribosylaminoimidazole Synthetase; Glycinamide Ribonucleotide Synthetase-Aminoimidazole Ribonucleotide Synthetase-Glycinamide Ribonucleotide Transformylase; Trifunctional Purine Biosynthetic Protein Adenosine-3; Glycinamide Ribonucleotide Formyltransferase; GAR Transformylase; PGFT; PRGS; GARS-AIRS-GART;
Biological Process
de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Adenine biosynthetic process Source: GO_Central
Brainstem development Source: Ensembl
Cerebellum development Source: Ensembl
Cerebral cortex development Source: Ensembl
Glycine metabolic process Source: Ensembl
Purine nucleotide biosynthetic process Source: GO_Central
Purine ribonucleoside monophosphate biosynthetic process Source: Reactome
Response to inorganic substance Source: Ensembl
Response to organic substance Source: Ensembl
Tetrahydrofolate biosynthetic process Source: Ensembl
Cellular Location
Cytosol; Extracellular exosome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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