Mouse Anti-FNTB Recombinant Antibody (3A9) (CBMAB-A3063-LY)

Name: Mouse Anti-FNTB Recombinant Antibody (3A9)
SKU: CBMAB-A3063-LY
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

3A9

Antibody Isotype

IgG2b, κ

Application

WB, ELISA

Basic Information

Immunogen

FNTB (AAH20232, 1 a.a. ~ 437 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

farnesyltransferase, CAAX box, beta

Entrez Gene ID

2342

UniProt ID

P49356

Alternative Names

FPTB; MGC31935

Function

Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.

Biological Process

Protein farnesylation Source: UniProtKB
Protein prenylation Source: GO_Central

Cellular Location

Microtubule associated complex; Cytosol; Protein farnesyltransferase complex

More Infomation

References

Bachmann, H. S., Jung, D., Link, T., Arnold, A., Kantelhardt, E., Thomssen, C., ... & Kuhlmann, J. D. (2022). FNTB promoter polymorphisms are independent predictors of survival in patients with triple negative breast cancer. Cancers, 14(3), 468.

Ding, J., Chen, Y. X., Chen, Y., Mou, Y., Sun, X. T., Dai, D. P., ... & Guo, X. (2020). Overexpression of FNTB and the activation of Ras induce hypertrophy and promote apoptosis and autophagic cell death in cardiomyocytes. Journal of Cellular and Molecular Medicine, 24(16), 8998-9011.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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