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Rat Anti-FKBP2 (AA 22-142) Recombinant Antibody (CBXF-2642) (CBMAB-F3062-CQ)


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Summary

Host Animal
Rat
Specificity
Human, Mouse, Rat
Clone
CBXF-2642
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
E. coli-derived recombinant human FKBP13, Ala22-Leu142, Accession # P26885
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with trehalose
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 22-142

Target

Full Name
FK506 Binding Protein 2
Introduction
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Entrez Gene ID
Human2286
Mouse14227
Rat293702
UniProt ID
HumanP26885
MouseP45878
RatD3ZZR9
Alternative Names
FK506 Binding Protein 2; FK506 Binding Protein 2, 13kDa; 13 KDa FK506-Binding Protein; Rapamycin-Binding Protein; Immunophilin FKBP13; Proline Isomerase; PPIase FKBP2; 13 KDa FKBP; Rotamase; FKBP-13;
Function
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Biological Process
Chaperone-mediated protein folding Source: InterPro
Cellular Location
Endoplasmic reticulum membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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