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Mouse Anti-FCRLB Recombinant Antibody (2F8) (CBMAB-A2912-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2F8
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
FCRLB (NP_689591.1, 89 a.a. ~ 174 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Fc receptor-like B
Introduction
FCRL2 belongs to the Fc receptor family. Fc receptors are involved in phagocytosis, antibody-dependent cell cytotoxicity, immediate hypersensitivity, and transcytosis of immunoglobulins via their ability to bind immunoglobulin (Ig) constant regions (Chikaev et al., 2005 [PubMed 15676285]).[supplied by OMIM
Entrez Gene ID
127943
UniProt ID
Q6BAA4
Alternative Names
FCRL2; FCRLM2; FCRLY; FLJ31052; FREB-2; FcRY; RP11-474I16.6
Biological Process
Cell surface receptor signaling pathway Source: GO_Central
Negative regulation of immune response Source: GO_Central
Cellular Location
Endoplasmic reticulum; Cytoplasm. Seems not to be secreted.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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