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Mouse Anti-FBXO21 Recombinant Antibody (CBXF-3622) (CBMAB-F2858-CQ)


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Summary

Host Animal
Mouse
Specificity
Human, Dog, Rat, Monkey
Clone
CBXF-3622
Antibody Isotype
IgG1
Application
FC, IF, IHC-P, WB

Basic Information

Immunogen
Full length human recombinant protein of human FBXO21 (NP_269373)
Specificity
Human, Dog, Rat, Monkey
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
0.61 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
F-Box Protein 21
Introduction
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
Entrez Gene ID
Human23014
Rat360818
Monkey693647
Dog486290
UniProt ID
HumanO94952
RatF1M5Q6
MonkeyA0A2K5UWF6
DogE2RKH1
Alternative Names
F-Box Protein 21; F-Box Only Protein 21; FBX21; KIAA0875;
Research Area
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Biological Process
Ubiquitin-dependent protein catabolic process Source: UniProtKB
Cellular Location
Cytosol; Ubiquitin ligase complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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