Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-DCXR Recombinant Antibody (6A6) (V2LY-0125-LY1276)


See all DCXR antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
6A6
Antibody Isotype
IgG1, κ
Application
ELISA, IHC-P, WB

Basic Information

Immunogen
DCXR (145-244aa) partial recombinant protein.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
IHC-P3 μg/mL

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Dicarbonyl And L-Xylulose Reductase
Entrez Gene ID
51181
UniProt ID
Q7Z4W1
Function
Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
Biological Process
D-xylose metabolic process Source: UniProtKB-KW
Glucose metabolic process Source: UniProtKB
Glucuronate catabolic process to xylulose 5-phosphate Source: Reactome
NADP metabolic process Source: Ensembl
Positive regulation of reactive oxygen species metabolic process Source: UniProtKB
Xylulose metabolic process Source: UniProtKB
Cellular Location
Membrane. Probably recruited to membranes via an interaction with phosphatidylinositol.
Involvement in disease
Pentosuria (PNTSU):
An inborn error of metabolism characterized by excessive urinary excretion of L-xylulose.
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-DCXR Recombinant Antibody (6A6)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry