Mouse Anti-CYTIP Recombinant Antibody (0254) (CBMAB-0254CQ)

Name: Mouse Anti-CYTIP Recombinant Antibody (0254)
SKU: CBMAB-0254CQ
Rating: 5 (1 reviews)

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Summary

Host Animal

Mouse

Specificity

Mouse, Rat

Clone

0254

Antibody Isotype

IgG2b, κ

Application

WB, IP, IF, ELISA

Basic Information

Immunogen

Amino acids 183-345 mapping near the C-terminus of mouse CYTIP.

Host Species

Mouse

Specificity

Mouse, Rat

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:100-1:1,000
IP	1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)
ELISA	1:100-1:1,000
IF(ICC)	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 0.1% gelatin

Preservative

< 0.1% sodium azide

Concentration

0.2 mg/ml

Target

Full Name

Cytohesin 1 Interacting Protein

Entrez Gene ID

227929

UniProt ID

Q91VY6

Function

By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.

Biological Process

Regulation of cell adhesion Source: MGI

Cellular Location

Early endosome; Cytoplasm. Recruited from the cytosol to endosomes by SNX27.

More Infomation

References

Queiroz, R. M., Piper, S., Rees, J. S., Strickson, S., Briend, E., Low, C. P., ... & Finch, D. K. (2022). Proteomic analysis in primary T cells reveals IL-7 alters T cell receptor thresholding via CYTIP/cytohesin/LFA-1 localisation and activation. Biochemical Journal.

Grosche, L., Draßner, C., Mühl-Zürbes, P., Kamm, L., Le-Trilling, V. T. K., Trilling, M., ... & Heilingloh, C. S. (2017). Human cytomegalovirus-induced degradation of CYTIP modulates dendritic cell adhesion and migration. Frontiers in immunology, 8, 461.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-CYTIP Recombinant Antibody (CBXC-1749)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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