Rabbit Anti-CST4 Recombinant Antibody (6) (V2LY-0125-LY122)

Name: Rabbit Anti-CST4 Recombinant Antibody (6)
SKU: V2LY-0125-LY122
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Rabbit

Specificity

Human

Clone

Antibody Isotype

IgG

Application

ELISA, IF, FC

Basic Information

Immunogen

Recombinant Human Cystatin S / CST4 protein.

Host Species

Rabbit

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal Antibody

Application Notes

Application	Note
ELISA	1:5,000-1:10,000
IF(ICC)	1:20-1:100
FC	1:25-1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Cystatin S

Entrez Gene ID

1472

UniProt ID

P01036

Function

This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.

Biological Process

Detection of chemical stimulus involved in sensory perception of bitter taste Source: UniProtKB
Negative regulation of proteolysis Source: UniProtKB
Retina homeostasis Source: UniProtKB

Cellular Location

Secreted

PTM

Phosphorylated at both its N- and C-terminal regions.

More Infomation

References

Wang, S., Wang, C., Liu, O., Hu, Y., Li, X., & Lin, B. (2021). Prognostic value of immune-related cells and genes in the tumor microenvironment of ovarian cancer, especially CST4. Life Sciences, 277, 119461.

Dou, Y., Lv, Y., Zhou, X., He, L., Liu, L., Li, P., ... & Wang, C. (2018). Antibody-sandwich ELISA analysis of a novel blood biomarker of CST4 in gastrointestinal cancers. OncoTargets and therapy, 11, 1743.

Martini, D., Gallo, A., Vella, S., Sernissi, F., Cecchettini, A., Luciano, N., ... & Baldini, C. (2017). Cystatin S—a candidate biomarker for severity of submandibular gland involvement in Sjögren’s syndrome. Rheumatology, 56(6), 1031-1038.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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