Mouse Anti-CREB5 Recombinant Antibody (8A5) (V2LY-1206-LY1117)

Name: Mouse Anti-CREB5 Recombinant Antibody (8A5)
SKU: V2LY-1206-LY1117
Rating: 5 (1 reviews)

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Summary

Host Animal

Mouse

Specificity

Human, Mouse

Clone

8A5

Antibody Isotype

IgG2a, κ

Application

WB, ELISA, IF, IHC-P

Basic Information

Immunogen

CREB5 (aa1-99) partial recombinant protein.

Host Species

Mouse

Specificity

Human, Mouse

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Application Notes

Application	Note
IF(ICC)	10 µg/ml
IHC	3 µg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

CREB5

Entrez Gene ID

Human	9586
Mouse	231991

UniProt ID

Human	Q02930
Mouse	Q8K1L0

Function

Binds to the cAMP response element and activates transcription.

Biological Process

Positive regulation of transcription, DNA-templated Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central

Cellular Location

Nucleus

More Infomation

References

Wang, S., Qiu, J., Liu, L., Su, C., Qi, L., Huang, C., ... & Liao, W. (2020). CREB5 promotes invasiveness and metastasis in colorectal cancer by directly activating MET. Journal of Experimental & Clinical Cancer Research, 39(1), 1-11.

Zhang, X., Xu, Y., Yamaguchi, K., Hu, J., Zhang, L., Wang, J., ... & Chen, W. (2020). Circular RNA circVAPA knockdown suppresses colorectal cancer cell growth process by regulating miR-125a/CREB5 axis. Cancer Cell International, 20(1), 1-11.

Zhang, M., Li, Y., Wang, H., Yu, W., Lin, S., & Guo, J. (2019). LncRNA SNHG5 affects cell proliferation, metastasis and migration of colorectal cancer through regulating miR-132-3p/CREB5. Cancer biology & therapy, 20(4), 524-536.

Wu, J., Wang, S. T., Zhang, Z. J., Zhou, Q., & Peng, B. G. (2018). CREB5 promotes cell proliferation and correlates with poor prognosis in hepatocellular carcinoma. International Journal of Clinical and Experimental Pathology, 11(10), 4908.

Yu, M., Du, G., Xu, Q., Huang, Z., Huang, X., Qin, Y., ... & Lu, C. (2018). Integrated analysis of DNA methylome and transcriptome identified CREB5 as a novel risk gene contributing to recurrent pregnancy loss. EBioMedicine, 35, 334-344.

He, S., Deng, Y., Liao, Y., Li, X., Liu, J., & Yao, S. (2017). CREB5 promotes tumor cell invasion and correlates with poor prognosis in epithelial ovarian cancer. Oncology Letters, 14(6), 8156-8161.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-CREB5 Recombinant Antibody (CBFYC-2199)

Mouse Anti-CREB5 Recombinant Antibody (CBFYC-2198)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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