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Mouse Anti-CNKSR3 Recombinant Antibody (CBLNC-142) (V2LY-1206-LY425)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLNC-142
Antibody Isotype
IgG2b, κ
Application
WB, ELISA, IP

Basic Information

Immunogen
CNKSR3 (366 a.a. ~ 464 a.a) partial recombinant protein.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
CNKSR family member 3
Entrez Gene ID
154043
UniProt ID
Q6P9H4
Function
Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression. Acts as a scaffold protein coordinating the assembly of an ENaC-regulatory complex (ERC).
Biological Process
Negative regulation of ERK1 and ERK2 cascade Source: UniProtKB
Negative regulation of peptidyl-serine phosphorylation Source: UniProtKB
Positive regulation of sodium ion transport Source: UniProtKB
Cellular Location
Apical cell membrane; Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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