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Rabbit Anti-CKM Recombinant Antibody (EG710) (CBMAB-EN864-LY)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG710
Antibody Isotype
IgG
Application
WB, IHC, IF, FC

Basic Information

Immunogen
Recombinant protein within Human Creatine kinase B type aa 27-118.
Host Species
Rabbit
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:500-1:2,000
IHC-P1:50-1:200
IF(ICC)1:50-1:200
FC1:50-1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
TBS, pH 7.4, 40% glycerol, 0.05% BSA
Preservative
0.05% sodium azide
Concentration
1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Creatine Kinase, M-Type
Introduction
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human1158
Mouse12715
Rat24265
UniProt ID
HumanP06732
MouseP07310
RatP00564
Alternative Names
Creatine Kinase, M-Type; Creatine Kinase, Muscle; Creatine Kinase M Chain; EC 2.7.3.2; CKMM; M-CK; Creatine Kinase M-Type; EC 2.7.3;
Function
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Biological Process
Creatine metabolic process Source: Reactome
Phosphocreatine biosynthetic process Source: GO_Central
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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