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Rabbit Anti-CEP43 Recombinant Antibody (CBXF-2990) (CBMAB-F3696-CQ)


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Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
CBXF-2990
Antibody Isotype
IgG
Application
IHC, WB

Basic Information

Immunogen
Synthetic peptide within human FGFR1OP aa 350-399.
Host Species
Rabbit
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:500
IHC1:400

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
TBS, pH7.4, 0.05% BSA, 40% Glycerol
Preservative
0.05% sodium azide
Concentration
1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-379

Target

Full Name
CEP43
Introduction
This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
Entrez Gene ID
11116
UniProt ID
O95684
Alternative Names
FGFR1 Oncogene Partner; FOP; Fibroblast Growth Factor Receptor 1 Oncogene Partner;
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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