Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-CCT7 Recombinant Antibody (1D6) (CBMAB-C5659-LY)


See all CCT7 antibodies
Online Inquiry
Published Data
CBMAB-C5659-LY-1
Mouse Anti-CCT7 Recombinant Antibody (1D6) (CBMAB-C5659-LY) in WB
Tandem FLAG and GFP pulldowns show preferential binding of TRiC to DDB1/CUL4A/RBX1-free CSA. CSA-FLAG, GFP, and GFP-DDB1 were expressed in U2OS cells as indicated. Enrichment of CSA-interacting proteins by means of FLAG pulldowns confirmed interactions between CSA and DDB1 and CUL4A, as well as the TRiC subunits CCT4 and CCT7. ...View More
Pines, A., Dijk, M., Makowski, M., Meulenbroek, E. M., Vrouwe, M. G., Van Der Weegen, Y., ... & van Attikum, H. (2018). TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A. Nature Communications, 9(1), 1040. Distributed under Open Access license CC BY 4.0, without modification.

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
1D6
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
CCT7 (425 a.a. ~ 528 a.a) partial recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
chaperonin containing TCP1, subunit 7 (eta)
Introduction
CCT7 (Chaperonin Containing TCP1 Subunit 7) is a Protein Coding gene. Diseases associated with CCT7 include Myocardial Infarction and Babesiosis. Among its related pathways are Chaperonin-mediated protein folding and Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding. Gene Ontology (GO) annotations related to this gene include identical protein binding and unfolded protein binding.
Entrez Gene ID
10574
UniProt ID
Q99832
Function
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444).
The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444).
The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Biological Process
Binding of sperm to zona pellucida Source: Ensembl
Positive regulation of establishment of protein localization to telomere Source: BHF-UCL
Positive regulation of protein localization to Cajal body Source: BHF-UCL
Positive regulation of telomerase RNA localization to Cajal body Source: BHF-UCL
Positive regulation of telomere maintenance via telomerase Source: BHF-UCL
Protein folding Source: FlyBase
Protein stabilization Source: BHF-UCL
Toxin transport Source: Ensembl
Cellular Location
Cytoplasm
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-CCT7 Recombinant Antibody (1D6)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry