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Mouse Anti-CARF Recombinant Antibody (1F7) (CBMAB-A4275-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1F7
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
CARF (1aa-579aa) Full length recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 621-718

Target

Full Name
Calcium Responsive Transcription Factor
Introduction
CARF (Calcium Responsive Transcription Factor) is a protein coding gene. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and transcriptional activator activity, RNA polymerase II proximal promoter sequ
Entrez Gene ID
79800
UniProt ID
Q8N187
Alternative Names
Calcium Responsive Transcription Factor; Calcium-Response Factor; Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 8 Protein; Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 8; Testis Development Protein NYD-SP24;
Function
Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.
Biological Process
Cellular response to calcium ion Source: UniProtKB
Cellular response to potassium ion Source: UniProtKB
Positive regulation of transcription from RNA polymerase II promoter in response to calcium ion Source: UniProtKB
Regulation of DNA-binding transcription factor activity Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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