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Mouse Anti-BUD31 Recombinant Antibody (CBYY-1795) (CBMAB-2144-YY)

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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat, Horse, Cattle, Pig, Dog
Clone
CBYY-1795
Antibody Isotype
IgG2a, κ
Application
WB, E, IP. IF, P

Basic Information

Immunogen
Amino acids 13-65 mapping near the N-terminus of BUD31 of human origin.
Host Species
Mouse
Specificity
Human, Mouse, Rat, Horse, Cattle, Pig, Dog
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000
IHC-P1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
0.09% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
BUD31 Homolog
Introduction
BUD31 (BUD31 Homolog) is a Protein Coding gene. Among its related pathways are Gene Expression and mRNA Splicing - Major Pathway. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity.
Entrez Gene ID
UniProt ID
Alternative Names
BUD31 Homolog; Functional Spliceosome-Associated Protein 17; Protein G10 Homolog; Protein EDG-2; EDG2; G10 Maternal Transcript Homolog (Xenopus Laevis); G10 Maternal Transcript Homolog; BUD31 Homolog (S. Cerevisiae); Maternal G10 Transcript;
Function
Involved in the pre-mRNA splicing process (PubMed:28502770, PubMed:28076346).
May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity (PubMed:25091737).
Biological Process
mRNA splicing, via spliceosome Source: UniProtKB
Positive regulation of androgen receptor activity Source: UniProtKB
Cellular Location
Nucleus. Detected in chromatin at the promoter of AR target genes.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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