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Mouse Anti-ALDOC Monoclonal Antibody (1A1) (CBMAB-0935-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
1A1
Antibody Isotype
IgG1
Application
ICC, IF, FC, WB

Basic Information

Immunogen
The C-terminal 23 amino acids of human Aldolase C (KYEGSGEDGGAAAQSLYIANHAY).
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:2,000-1:5,000
IF(ICC)1:1,000-1:2,000
FC1 µg/10^6 cells

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% PBS, 50% glycerol
Preservative
5mM sodium azide
Concentration
1 mg/ml
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
Located in C-Terminal

Target

Full Name
Aldolase, Fructose-Bisphosphate C
Introduction
Aldolase, fructose-bisphosphate C (ALDOC) is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. ALDOC is a member of the class I fructose-biphosphate aldolase gene family which is expressed specifically in the hippocampus and Purkinje cells of the brain.
Entrez Gene ID
Human230
Mouse11676
Rat24191
Cattle504584
Pig100512013
UniProt ID
HumanP09972
MouseP05063
RatP09117
CattleA0A3S5ZPB0
PigA0A287B8Z2
Alternative Names
ALDC
Biological Process
Canonical glycolysis Source: Reactome
Epithelial cell differentiation Source: UniProtKB
Fructose 1,6-bisphosphate metabolic process Source: UniProtKB
Fructose metabolic process Source: ProtInc
Gluconeogenesis Source: Reactome
Glycolytic process Source: GO_Central
Neutrophil degranulation Source: Reactome
Cellular Location
Cytoskeleton; Cytosol; Extracellular exosome; Extracellular region; Ficolin-1-rich granule lumen; Secretory granule lumen; Tertiary granule lumen
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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