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Mouse Anti-LRFN1 Recombinant Antibody (CBYJL-1951) (CBMAB-L2013-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJL-1951
Antibody Isotype
IgG2b
Application
IHC

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 32-534

Target

Full Name
leucine rich repeat and fibronectin type III domain containing 1
Introduction
Among LRFN1's related pathways are Protein-protein interactions at synapses and Transmission across Chemical Synapses. An important paralog of this gene is LRFN2.
Entrez Gene ID
57622
UniProt ID
Q9P244
Alternative Names
SALM2; leucine-rich repeat and fibronectin type III domain-containing protein 1; CTC-246B18.8; synaptic adhesion-like molecule 2
Function
Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1 (By similarity).
Biological Process
Membrane
Cell junction, synapse
Cell junction, synapse, postsynaptic density membrane
Detected in excitatory, but not inhibitory, synaptic plasma membrane.
Topology
Extracellular: 32-536
Helical: 537-557
Cytoplasmic: 558-771
PTM
Glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

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